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Periodic fever, aphthous stomatitis, pharyngitis and adenitis or periodic fever aphthous pharyngitis and cervical adenopathy (PFAPA) syndrome is a medical condition, typically starting in young children, in which high fever occurs periodically at intervals of about 3–5 weeks, frequently accompanied by aphthous-like ulcers,pharyngitis, and/or cervical adenitis (cervical lymphadenopathy). The syndrome was described in 1987 and named two years later.
The key symptoms of PFAPA are those in its name: periodic high fever at intervals of about 3–5 weeks, as well as aphthous ulcers,pharyngitis and/or adenitis. In between episodes, and even during the episodes, the children appear healthy.
PFAPA syndrome typically resolves spontaneously. Treatment options are used to lessen the severity of episodes. Treatment is either medical or surgical.
Gulvalex Capsule 1 three times a day when given for 7 to 21 days improves the conditions,lowers the tempreture,imparts anti-inflammatory effect on pharynx and adenoid glands.This regimin usually ends the fever within few days.
According to present research, PFAPA does not lead to other diseases and spontaneously resolves as the child gets older, with no long term physical effects. However, PFAPA has been found in adults and may not spontaneously resolve. Medical treatment for PFAPA for adults is same but in enhanced dosage schedule.